Lucia Mazzacurati, PhD

  • Postdoctoral Associate

Why did you choose the University of Pittsburgh?

I found my graduate school program very interesting. Also University of Pittsburgh is a very good place to do high quality research.

Following her graduation, Lucia accepted a postdoctoral associate position in the Department of Pathology here at the University of Pittsburgh.

Education & Training

  • PhD in Human Genetics, University of Pittsburgh, Graduate School of Public Health, 2012
  • Honor Degree (equal to BSc+MSc) in Biotechnology, University of Bologna (Italy)

Publications

A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation. Oncogene. 27: 5243-5253. |  View abstract

K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis. PLoS One. 2: e1067. |  View abstract

Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13. Oncogene. 26: 1656-1660. |  View abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J. Biol. Chem. 282: 24858-24865. |  View abstract

Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase. Leuk. Res. 28: 191-202. |  View abstract