Lucia Mazzacurati, PhD

Postdoctoral Associate




PhD in Human Genetics, University of Pittsburgh, Graduate School of Public Health, 2012

Honor Degree (equal to BSc+MSc) in Biotechnology, University of Bologna (Italy)


Human Genetics (GSPH)


Paola Grandi, PhD


Areas of Interest

Virology, Oncology

Why I Chose Pitt

I found my graduate school program very interesting. Also University of Pittsburgh is a very good place to do high quality research.

Following her graduation, Lucia accepted a postdoctoral associate position in the Department of Pathology here at the University of Pittsburgh.


Mazzacurati L, Marzulli M, Reinhart B, Cohen JB, Glorisos JC, Grandi P. MicroRNA Control of HSV-1 Replication for the Treatment of Glioblastoma Multiforme. ASGCT 2011 Annual Meeting


A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation. Oncogene. 27: 5243-5253. |  View Abstract

K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis. PLoS One. 2: e1067. |  View Abstract

Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13. Oncogene. 26: 1656-1660. |  View Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J. Biol. Chem. 282: 24858-24865. |  View Abstract

Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase. Leuk. Res. 28: 191-202. |  View Abstract

Chk2 drives late G1/early S phase arrest of clonal myeloid progenitors expressing the p210 BCR-ABL tyrosine kinase in response to STI571. Hematol. J. 5: 168-177. |  View Abstract

The p210BCR-ABL tyrosine kinase of chronic myeloid leukemia causes resistance to radio-induced apoptotic death by inhibiting the proapoptotic BAX gene. Leukemia. 18: 370-372. |  View Abstract