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Malcolm Meyn III, Ph.D.
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Research Assistant Professor
E1209 BSTWR
200 Lothrop Street
Pittsburgh, Pennsylvania 15261
Phone: (412) 648-9240
Fax: (412) 624-1401
E-mail: mam71@pitt.edu
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Biography
Dr. Meyn is a Research Assistant Professor in the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine. Dr. Meyn received his Ph.D. from the University of Arizona. He completed postdoctoral training in the Howard Hughes Medical Institute at the University of Pennsylvania and at the University of Pittsburgh.
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Selected Publications
- Meyn MA 3rd, Smithgall TE. 2009. Chemical Genetics Identifies c-Src as an Activator of Primitive Ectoderm Formation in Murine Embryonic Stem Cells. Science Signaling 2, ra64.| Abstract | Associated Podcast
- Engen JR, Wales TE, Hochrein JM, Meyn MA 3rd, Banu Ozkan S, Bahar I, Smithgall TE. 2008. Structure and dynamic regulation of Src-family kinases. Cellular and Molecular Life Sciences 65:3058-73. | Abstract | Citations
- Meyn MA 3rd, Smithgall TE. 2008. Small molecule inhibitors of Lck: the search for specificity within a kinase family. Mini Reviews in Medicinal Chemistry 8:628-37. | Abstract | Citations
- Meyn, M.A., Wilson, M.B., Abdi, F.A., Fahey, N., Schiavone, A.P., Wu, J., Hochrein, J.M., Engen, J.R. and Smithgall, T.E. 2006. Src Family Kinases Phosphorylate the Bcr-Abl SH3-SH2 Region and Modulate Bcr-Abl Transforming Activity. Journal of Biological Chemistry 281:30907-16. | Abstract | Citations | Faculty of 1000 Citation
- Meyn, M.A., Schreiner, S.J., Dumitrescu, T.P., Nau, G.J. and Smithgall, T.E. 2005. Src kinase activity is required for murine embryonic stem cell growth and differentiation. Molecular Pharmacology 68:1320-1330. | Abstract | Citations
- Meyn, M.A., Melloy, P.M., Li, J., and Holloway, S.L. 2002. The destruction box of the cyclin Clb2 binds the anaphase promoting complex/cyclosome subunit Cdc23. Archives of Biochemistry and Biophysics /407:189-195. | Abstract | Citations
- Hendrickson, C.H., Meyn, M.A., Morabito, L., and Holloway, S.L. 2001. The KEN box regulates Clb2 proteolysis in G1 and at the metaphase to anaphase transition. Current Biology 11:1781-1787. | Abstract | Citations
- Meyn, M.A. and S. L. Holloway. 2000. S phase cyclins are required for a stable arrest at metaphase. Current Biology 10:1599-1602. | Abstract | Citations
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