Xian Wang
- Research Project Manager
Why did you choose the University of Pittsburgh?
Outstanding research resources and exceptional lab atmosphere
Education & Training
- PhD, Functional Geonomics, North Carolina University, US, 2012
- BS in Biotechnology, Sichuan University, China, 2003
Research Interests
I'm interested in translational cancer research by using in vitro and in vivo mouse models. I am currently working on projects to investigate the function of a potential novel tumor suppressor in transgenic and syngeneic mouse models.
Publications
Wang X, Veeraraghavan J, Liu C-C, Cao X, Qin L, Kim J, Tan Y, Loo SK, Hu Y, Lin L, Lee S, Shea M, Mitchell T, Li S, Ellis M, Hilsenbeck S, Schiff R, Wang X. 2021. Therapeutic Targeting of Nemo-Like Kinase in Primary and Acquired Endocrine-resistant Breast Cancer. Clinical Cancer Research, 27, 9: 2648-2662. doi:10.1158/1078-0432 | View abstract
Li T, Wang X, Zhang X, Ju E, Wei S, da Silva SR, Chen L, Gao S-J. 2021. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nature Communication, 12,1: 1055. doi:10.1038/s41467-021-21206-3 | View abstract
Wang X, Tan Y, Cao X, Kim JA, Chen T, Hu Y, Wexler M, Wang X. 2018. Epigenetic activation of HORMAD1 in basal-like breast cancer: role in PARP inhibitor sensitivity. Oncotarget 9, 53:30115-30127. doi: 10.18632/oncotarget.25728 | View abstract
Wang X, Cadenas M, Sistrunk C, Paula L. Miliani de Marval and Marcelo L Rodriguez-Puebla. 2012. Combined effect of cyclin D3 and cyclin D1 inhibit mouse skin tumor development. The Cell Cycle, 11,2:335-42. doi: 10.4161/cc.11.2.18774 | View abstract
Wang X, Chris Sistrunk and Marcelo Rodriguez-Puebla. 2011. Unexpected Reduction of Skin Tumorigenesis upon Expression of Cyclin-Dependent Kinase 6 in mouse epidermis. American Journal of Pathology, 178,1:345-54. doi: 10.1016/j.ajpath.2010.11.032 | View abstract