Jihong Li, PhD
- Research Instructor
Education & Training
- PhD in Molecular Biology, Hainan University (China), 1997
- BSc in Biology, Lanzhou University (China), 1991
Research Interests
I have conducted research on the pathogenesis of Clostridium perfringens diseases since 2005. My long-term interest has concerned understanding the molecular epidemiology and pathogenesis of C. perfringens, including toxin regulation and action during C. perfringens infections. I am particularly interested in understanding the contribution of sialidases to C. perfringens growth and pathogens.
Research Lab Affiliation
McClane Lab
Publications
Freedman JC, Li J, Mi E and McClane BA. 2019. Identification of an important orphan histidine kinase for the initiation of sporulation and enterotoxin production by Clostridium perfringens type F strain SM101. mBio. 10: e02674-18. | View abstract
Li J and McClane BA. 2018. NanI sialidase can support the growth and survival of Clostridium perfringens strain F4969 using sialyated host macromolecules (Mucin) or Caco-2 Cells. Infect Immun. 86: pii: e00547-17. | View abstract
Li J, Ma M, Sarker MR and McClane BA. 2013. CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718. mBio. 4: e00770-13. | View abstract
Li J, Sayeed S, Robertson S, Chen J and McClane BA. 2011. Sialidases affect the host cell adherence and epsilon toxin-induced cytotoxicity of Clostridium perfringens type D strain CN3718. PLoS Pathog. 7: e1002429. | View abstract
Li J, Adams V, Bannam TL, Miyamoto K, Garcia JP, Uzal FA, Rood JI and McClane BA. 2013. Toxin Plasmids of Clostridium perfringens. Microbiol Mol Biol Rev. 77: 208-233. | View abstract