Chandra Nath Roy, PhD
- Research Scientist
Why did you choose the University of Pittsburgh?
University of Pittsburgh is one of the top ranked universities in the USA having state-of-the-art multidiscplinary basic and translational research facilities. Pittsburgh City is an excellent place to live.
Education & Training
- PhD in Virology, Tohoku University Graduate School of Medicine (Japan), 2015
- MSc: Institute of Nutrition and Food Science, Dhaka University (Bangladesh), 2002
- MBBS (Bachelor of Medicine and Bachelor of Surgery), Dhaka University (Bangladesh), 2000
Research Interests
Transmission and prevention of drug-resistant HIV, Establishment and persistence of HIV reservoirs, HIV-1 Animal models, drug development and testing for HIV-1 and other emerging viarl infectious diseases, recombinant oncolytic virus-based cancer therapy
Publications
Roy CN, Benitez Moreno MA, Kline C and Ambrose Z. (2021) CG Dinucleotide Removal in Bioluminescent and Fluorescent Reporters Improves HIV-1 Replication and Reporter Gene Expression for Dual Imaging in Humanized Mice. J Virol. 95: e0044921. doi: 10.1128/JVI.00449-21. Epub 2021 Sep 9.
Melody K, Roy CN, Kline C, Cottrell ML, Evans D, Shutt K, Pennings PS, Keele BF, Bility M, Kashuba ADM and Ambrose Z. (2020) Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice. J Virol. 94: e01912-19. doi: 10.1128/JVI.01912-19.
Forero A, Ozarkar S, Li H, Lee CH, Hemann EA, Nadjsombati MS, Hendricks MR, So L, Green R, Roy CN, Sarkar SN, von Moltke J, Anderson SK, Gale M Jr and Savan R. (2019) Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons. Immunity. 51: 451-464.e6. doi: 10.1016/j.immuni.2019.07.007. Epub 2019 Aug 27.
Roy CN, Khandaker I and Oshitani H. (2015) Evolutionary Dynamics of Tat in HIV-1 Subtypes B and C. PLoS One. 10: e0129896. doi: 10.1371/journal.pone.0129896.
Suzuki Y, Roy CN, Promjunyakul W, Hatakeyama H, Gonda K, Imamura J, Vasudevanpillai B, Ohuchi N, Kanzaki M, Higuchi H and Kaku M. (2013) Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis. Mol Cell Biol. 33: 3036-3049. doi: 10.1128/MCB.01717-12. Epub 2013 Jun 3.